The battle of Andros is one of the more obscure naval battles of the Hellenistic era. It was fought between a Macedonian fleet under Antigonus “the old man”, and an Egyptian fleet, close to the important Egyptian naval base on Andros. The date of 246 BC is not certain, and is partly based on the establishment of two vase festivals at Delos in 245 BC by Antigonus II Gonatas to celebrate an unknown victory. This date would place the battle as taking place during the Third Syrian War (246-241 BC), between Ptolemaic Egypt and the Seleucid Empire. Although Macedonia is not known to have taken part directly in that war, that does not preclude this date.
The result of the battle is known. The Macedonian fleet, under the command of Antigonus, defeated a larger Egyptian fleet, under a commander called Sophron. The defeat seems to have ended serious Egyptian interest in the Aegean, although she still possessed a powerful fleet, which played a part in the Third Syrian War, as well as limited possessions in the area, including the island of Thera.